1.Why Drug Capsules A capsule is just a coat or vest of […]
1.Why Drug Capsules
A capsule is just a coat or vest of a drug. Of course, the purpose of using it is not just to make the drug look good, but mainly to make the drug easy to take and achieve the best effect.
Medications taken when you are sick are digested and absorbed into the bloodstream by the gastrointestinal tract and broken down by the liver. However, quite a lot of powder, granule, liquid and tablet drugs are bitter and irritating, or they are easy to volatilize, or they are easily broken down by saliva in the mouth, and some drugs also inhale into the trachea, causing side effects. Therefore, capsules can protect the mouth and digestive tract, and are easy to swallow. To make the drug work best, it is also necessary to prevent the drug from being destroyed by human stomach acid. Because some drugs need to be dissolved and absorbed in the intestine, special membrane materials (such as gelatin, cellulose, polysaccharides, etc.) need to be made. Capsules, powder, liquid and other drugs are filled into the capsule according to the dose. In addition, drugs have a half-life, which refers to the time required for the drug's highest concentration in the blood to be reduced by half. The half-life of a drug reflects the rate of elimination (excretion, biotransformation, storage, etc.) of the drug in the body, showing the relationship between the time the drug is in the body and the blood drug concentration. Therefore, it is the main basis for determining the dosage and frequency of administration. Drugs with a long half-life are eliminated slowly in the body, and the interval between administrations is long; while drugs with a short half-life are eliminated in the body, the administration time is short. For drugs with a short half-life, frequent medication is required to maintain the concentration of the drug in the blood. To avoid the trouble of frequent medication, special capsules need to be used to wrap the drug. This is a slow-release capsule. Sustained-release capsule drugs can also avoid the shortcomings of frequent drug concentration fluctuations in the blood after frequent administration of the general preparations, resulting in the effective blood drug concentration fluctuating, and the side-effects of the sustained-release capsules are smaller than the general preparations. Therefore, many drugs, such as ibuprofen, aspirin, and Tylenol, have sustained-release capsule preparations.
2. Plant capsules are hope
Professionals have suggested that plant gelatin can be used in place of traditional gelatin to reduce the chances of illegal enterprises using industrial gelatin. Moreover, the use of plant capsules can also meet the requirements of ethnic and vegetarian people with certain religions in the world who cannot take medicines of animal materials (animal capsules), and at the same time avoid cross-infection of some pathogens, such as the spread of mad cow disease.
Plant capsules are rich in raw materials, such as carrageenan starch, malt extract, various celluloses, alginates, beeswax, etc., and some plasticizers, such as glycerin, sorbitol, maltitol, propylene glycol, polyethylene glycol and Water etc. Judging from the development of gelatin, traditional capsules (animal capsules) have been developed since the 1930s, and today they have only formed the main packaging form of pharmaceuticals. The research on plant capsules is only 20 years up to now. As long as breakthroughs are made in technology, equipment and raw materials, plant capsules will be of great use. Because it has not only a wide range of uses, but also good security.