How to eat capsules


Capsule drugs are the most common form of pharmaceutica […]

Capsule drugs are the most common form of pharmaceutical dosage form. Many people will be confused when they take it. "What can I do if I can't swallow it? Can I pour out the medicine in the capsule?" In fact, the reason why the medicine is contained in the capsule is to facilitate swallowing. There are also reasons for efficacy and safety.

Capsules are usually made up of the following reasons: first, it acts as a sub-agent, and is convenient to take; second, the drug itself is very bitter or odorous, and the capsule wrap can effectively mask the taste of the drug; third, the controlled empty capsules can continuously release the drug for a long time, or release the drug slowly at a predetermined rate, so that the blood concentration is stable. Fourth, the enteric capsule can prevent the drug from being destroyed by gastric acid, making it weakly alkaline in the intestine. Under absorption, on the one hand, it can better exert its effects, on the other hand, it can also avoid some adverse reactions.

If you take a regular capsule drug that acts as a granule, then pour the drug out of the capsule and it usually does not have much effect.

1. Enteric-coated capsules. A drug that is easily destroyed in the stomach and is irritating to the stomach is made into an enteric-coated capsule whose capsule shell is insoluble in gastric juice and dissolves and releases the drug after reaching the intestinal tract. The purpose is to prevent the drug from being destroyed by stomach acid or to prevent the drug from irritating the stomach. If forced removal is easy to reduce the effect of the drug, it may cause irritation to the stomach, which may cause stomach bleeding. For example, minocycline capsules, the instructions clearly indicate: "This product can cause esophageal ulcers when it is retained in the esophagus and disintegrates."

2. A drug with a particularly strong smell. Some drugs smell a lot and taste very bitter, which is difficult for adults to accept, let alone children. Disintegration of drugs can easily cause nausea and resentment in children, which can lead to fear of drugs. Commonly used antibiotics have a bitter taste, such as amoxicillin and cefradine. In fact, most of the drugs currently used for children will be made into granules and powders. If the taste is high, the taste-masking agent and fruity taste will be added appropriately to improve the discomfort of the child.

3. Sustained-release capsules or controlled-release capsules. These drugs must be swallowed in order to release the drug in a balanced dose for optimal efficacy. When taken apart, it will lose its slow and controlled release function, so that the drug will be released in a short time, the blood drug concentration will increase greatly, and even cause drug poisoning.